Malignancy and the Small-intestinal Mucosa

Malignancy and the Small-intestinal Mucosa.

The observations presented here suggest that malignancy anywhere in the body may be accompanied by a secondary change in the small-intestinal mucosa, including the flattened appearance that is usually seen in idiopathic steatorrhoea. The reverse of this association, that idiopathic steatorrhoea may be complicated by a reticulosis, has been reported by Gough et al. (1962). They described four ca...

Significance of a Flat Small-intestinal Mucosa.

Glycoprotein Biosynthesis in Small Intestinal Mucosa

An active multiglycosyltransferase system involved in the transfer of N-acetylgalactosamine, N-acetylglucosamine, and galactose to various glycoprotein acceptors was found in the rat small intestinal mucosa. The present studies are concerned with the subcellular localization of these glycosyltransferases. Satisfactory isolation of smooth and rough surfaced microsomes from the intestinal mucosa ...

Protein loss and cell loss from the small-intestinal mucosa.

Total protein and deoxyribonucleic acid (dna) were measured in small-intestinal washings from rats with normal and high rates of dna (or cell) loss. There was a significant relationship between the loss of these two substances. Preparations of isolated viable epithelial cells contained much less protein in relation to dna than did the intestinal washings. It was calculated that only 8 to 15% of...

Cryptosporidium, chronic diarrhoea and the proximal small intestinal mucosa.

The association between Cryptosporidium, chronic diarrhoea and a proximal small intestinal mucosal enteropathy was reviewed over a six and a half year period. One hundred and twenty three children with cryptosporidiosis and no clinical evidence of immune deficiency were identified. 50% of children excreting only Cryptosporidium had chronic diarrhoea. Most cases (63%) of chronic diarrhoea occurr...